GBS (Group B Streptococcus)

Max_078webGroub B Streptococcus (GBS, Streptococcus agalactiae) is the leading cause of life-threatening infections in newborns. Rapid and sensitive detection of neonatal infections and initiation of appropriate treatment is needed to minimize morbidity and mortality among newborns. PCR has proved to be a useful diagnostic tool due to its increased sensitivity and specificity and fast results.

For prenatal screening, the accuracy and timing of testing is important to prevent unnecessary use of intrapartum antibiotic prophylaxis (IAP).

The GenomEra® GBS assay simplifies and speeds up GBS testing by providing reliable results from enriched broth samples in less than one hour. The assay is suitable for both over-night and quick 4 h cultured broth enrichment samples and also for positive blood cultures.

Clinical performance

Over-night enrichment broth samples
Sensitivity: 97/99 = 98.0%
Specificity: 288/293 = 98.3%

Short 4 h enrichment broth samples
Sensitivity: 27/28= 96.4%
Specificity: 83/86 = 96.5%

Assay steps for broth cultures:

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Dispense suspension into tube and vortex.

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Pipette 35 ul to the test chip.

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Start the GenomEra® CDX assay run.