Recent publication: GenomEra C. difficile test demonstrates increased reliability for standalone molecular diagnostics

Posted 11 months ago on

While covid19 is spreading, there are still other worries to deal with. Standalone PCR testing for C. difficile diagnostics is often criticized for overdiagnosis of CDI. In a recent publication (doi:10.1128/JCM.01872-19) GenomEra routine samples were retested with two different toxin immunoassays and discrepant results were confirmed with culture or GeneXpert. Results shows perfect 100% PPV and excellent 99.7% NPV for GenomEra. Study reports insufficient sensitivities of 81.6% and 71.7% for two different toxin immunoassay from ArcDia and TechLab, respectively.