Toxin producing Clostridium difficile is a gram-positive, anaerobic, spore-forming bacterium. It is the most serious cause of antibiotic-associated diarrhoea (AAD) and the most common cause of pseudomembranous colitis. Symptoms of C. difficile-associated disease (CDAD) often begin after medication with antibiotics.
Diagnosing toxigenic C. difficile infection is a challenge in many clinical microbiology laboratories because of poor performance of rapid tests, increasing testing costs and complicated algorithms.
The GenomEra® C. difficile from Abacus Diagnostica offers a rapid, simple and high performance molecular assay to diagnose your patients directly from unformed stool samples suspected positive for toxigenic C. difficile in less than one hour.
Sensitivity: 97/98 = 99.0%
Specificity: 222/224 = 99.1%
Assay steps for stool samples:
Pick stool into the z-tube and vortex.
Pipette 35 ul to the test chip.
Start the GenomEra CDX assay run.
- Identifies the toxin B gene in < 1 h
- Molecular detection allows significantly faster outcome
- Fast and high performance results without excessive costs