C. difficile

Clostridium_isokuva

Toxin producing Clostridium difficile is a gram-positive, anaerobic, spore-forming bacterium. It is the most serious cause of antibiotic-associated diarrhoea (AAD) and the most common cause of pseudomembranous colitis. Symptoms of C. difficile-associated disease (CDAD) often begin after medication with antibiotics.

Diagnosing toxigenic C. difficile infection is a challenge in many clinical microbiology laboratories because of poor performance of rapid tests, increasing testing costs and complicated algorithms.

The GenomEra® C. difficile from Abacus Diagnostica offers a rapid, simple and high performance molecular assay to diagnose your patients directly from unformed stool samples suspected positive for toxigenic C. difficile in less than one hour.

Clinical performance

Sensitivity: 97/98 = 99.0%
Specificity: 222/224 = 99.1%

Assay steps for stool samples:

(tutorial video can be found here)

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Pick stool into the Z-tube and vortex.

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Pipette 35 ul to the test chip.

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Start the GenomEra® CDX assay run.

  • Identifies the toxin B gene in < 1 h
  • Molecular detection allows significantly faster outcome
  • Fast and high performance results without excessive costs